That is a cruddy still frame of Drew Carey, Slash… and Joey Ramone!
It was from season 4, episode 2, of The Drew Carey Show show entitled, “In Ramada Da Vida”.
The plot line called for open auditions for a guitarist to join Drew and company’s garage band.
If you haven’t seen the clip, I don’t want to ruin the surprises of who else shows up… but this is a moment of TV history that gathered a serious amount of talent into a montage for a well-written gag. Props to all the musicians for having the sense of humor to play along…